Genetic characterisation of molecular targets in carcinoma of unknown primary

Genetic characterisation of molecular targets in carcinoma of unknown primary

Abstract Background Carcinoma of unknown primary (CUP) is a metastatic epithelial malignancy in the absence of an identifiable primary tumour. Prognosis for patients with CUP is poor because treatment options are generally limited to broad spectrum chemotherapy. A shift towards personalised cancer m...

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Bibliographic Details
Main Authors: B. Clynick, B. Dessauvagie, G. Sterrett, N. T. Harvey, R. J. N. Allcock, C. Saunders, W. Erber, K. Meehan
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Translational Medicine
Subjects:
Carcinoma of unknown primary
CUP
Next-generation sequencing
Mutation profiling
Druggable targets
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s12967-018-1564-x

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http://link.springer.com/article/10.1186/s12967-018-1564-x

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