Norcholic Acid Promotes Tumor Progression and Immune Escape by Regulating Farnesoid X Receptor in Hepatocellular Carcinoma

Norcholic Acid Promotes Tumor Progression and Immune Escape by Regulating Farnesoid X Receptor in Hepatocellular Carcinoma

Accumulating evidence shows a close association between various types of bile acids (BAs) and hepatocellular carcinoma (HCC), and they have been revealed to affect tumor immune response and progression mainly by regulating Farnesoid X receptor (FXR). Nevertheless, the roles of Norcholic acid(NorCA)...

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Bibliographic Details
Main Authors: Yihang Gong, Kun Li, Yunfei Qin, Kaining Zeng, Jianrong Liu, Shaozhuo Huang, Yewu Chen, Haoyuan Yu, Wei Liu, Linsen Ye, Yang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma (HCC)
bile acids
exosomes
immune microenvironment
Farnesoid X receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.711448/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.711448/full

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