Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching
Abstract Fluorescent labeling of proteins is a powerful tool for probing structure-function relationships with many biosensing applications. Structure-based rules for systematically designing fluorescent biosensors require understanding ligand-mediated fluorescent response mechanisms which can be ch...
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Nature Portfolio
2023-08-01
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| coleção: | Communications Chemistry |
| Acesso em linha: | https://doi.org/10.1038/s42004-023-00982-7 |