The sequence of the repetitive motif influences the frequency of multistep mutations in Short Tandem Repeats
Abstract Microsatellites, or Short Tandem Repeats (STRs), are subject to frequent length mutations that involve the loss or gain of an integer number of repeats. This work aimed to investigate the correlation between STRs’ specific repetitive motif composition and mutational dynamics, specifically t...
Main Authors: | Sofia Antão-Sousa, Nádia Pinto, Pablo Rende, António Amorim, Leonor Gusmão |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-32137-y |
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