Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice

Aging results in chronic systemic inflammation that can alter neuroinflammation of the brain. Specifically, microglia shift to a pro-inflammatory phenotype predisposing them to hyperactivation upon stimulation by peripheral immune signals. It is proposed that certain nutrients can delay brain aging...

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Bibliographic Details
Main Authors: Stephanie M. Matt, Jacob M. Allen, Marcus A. Lawson, Lucy J. Mailing, Jeffrey A. Woods, Rodney W. Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01832/full