Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy
<p>Abstract</p> <p>Background</p> <p>In affected sibling pair linkage analysis, the presence of linkage disequilibrium (LD) has been shown to lead to overestimation of the number of alleles shared identity-by-descent (IBD) among sibling pairs when parents are ungenotype...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-08-01
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| Series: | BMC Genetics |
| Online Access: | http://www.biomedcentral.com/1471-2156/10/44 |