Mapping Proteome and Lipidome Changes in Early-Onset Non-Alcoholic Fatty Liver Disease Using Hepatic 3D Spheroids

Mapping Proteome and Lipidome Changes in Early-Onset Non-Alcoholic Fatty Liver Disease Using Hepatic 3D Spheroids

Non-alcoholic fatty liver disease affects one-fourth of the world’s population. Central to the disease progression is lipid accumulation in the liver, followed by inflammation, fibrosis and cirrhosis. The underlying mechanism behind the early stages of the disease is poorly understood. We have expos...

Full description

Bibliographic Details
Main Authors: Helle Sedighi Frandsen, Joel Mario Vej-Nielsen, Lauren Elizabeth Smith, Lang Sun, Karoline Lindgaard Mikkelsen, Annemette Præstegaard Thulesen, Christina Erika Hagensen, Fuquan Yang, Adelina Rogowska-Wrzesinska
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
3-dimensional cell culture
spheroids
human hepatocytes
fatty liver disease
NAFLD
steatosis
Online Access:https://www.mdpi.com/2073-4409/11/20/3216

Internet

https://www.mdpi.com/2073-4409/11/20/3216

Similar Items