Chemical Space of Fluorinated Nucleosides/Nucleotides in Biomedical Research and Anticancer Drug Discovery

Fluorinated nucleos(t)ide drugs have proven to be successful chemotherapeutic agents in treating various cancers. The Food and Drug Administration (FDA) has approved several drugs that fit within the fluorinated nucleoside pharmacophore, and many more are either in preclinical development or clinica...

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Bibliographic Details
Main Authors: Yugandhar Kothapalli, Tucker A. Lesperance, Ransom A. Jones, Chung K. Chu, Uma S. Singh
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Chemistry
Subjects:
Online Access:https://www.mdpi.com/2624-8549/7/1/7