In Vivo Validation of a Nanostructured Electrospun Polycaprolactone Membrane Loaded with Gentamicin and Nano-Hydroxyapatite for the Treatment of Periodontitis

In Vivo Validation of a Nanostructured Electrospun Polycaprolactone Membrane Loaded with Gentamicin and Nano-Hydroxyapatite for the Treatment of Periodontitis

The aim of this research was to validate the use of a gentamicin (GEN) and nano-hydroxiapatite (nHAP)-loaded polycaprolactone nanostructured membrane (NM) as an innovative, highly efficient, low-cost treatment for periodontitis. We conducted an in vivo study on Wistar rats, in which we induced perio...

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Bibliographic Details
Main Authors: Patricia Ondine Lucaciu, Călin Cosmin Repciuc, Ioana A. Matei, Nicodim I. Fiț, Sanda Andrei, Raluca Marica, Bianca Nausica Petrescu, Bogdan Crișan, Ovidiu Aghiorghiesei, Ioana Codruța Mirică, Dragoș Apostu, Codruța Saroși, Florin Onișor, Evelyn Vanea, Simina Angela Lăcrimioara Iușan, Giorgiana Corina Mureșan, Ana-Maria Condor, Emilia Oprița, Luciana-Mădălina Gherman
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Membranes
Subjects:
periodontitis
membrane
gentamicin
nano-hydroxyapatite
drug delivery system
Online Access:https://www.mdpi.com/2077-0375/14/3/60

Internet

https://www.mdpi.com/2077-0375/14/3/60

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