Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events

Unprecedented successes regarding cancer immunotherapy have been achieved, in which therapeutic agents are used to target immune cells rather than cancer cells. The most effective immunotherapy to date is the group of immune checkpoint inhibitors (CPI), targeting, for example, cytotoxic T-lymphocyte...

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Bibliographic Details
Main Authors: Esmée P. Hoefsmit, Elisa A. Rozeman, John B. A. G. Haanen, Christian U. Blank
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/4/4/e000472.full