In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice

In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice

Heavy metal exposure leads to multiple system dysfunctions. The mechanisms are likely multifactorial and involve inflammation and oxidative stress. The aim of this study was to evaluate markers and risk factors for atherosclerosis in the LDL receptor knockout mouse model chronically exposed to inorg...

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Bibliographic Details
Main Authors: Maiara I.C. Queiroz, Carolina M. Lazaro, Lohanna M.B. dos Santos, Thiago Rentz, João V. Virgilio-da-Silva, Pedro M.M. Moraes-Vieira, Francisco A.S. Cunha, Josué C.C. Santos, Anibal E. Vercesi, Ana Catarina R. Leite, Helena C.F. Oliveira
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Mercury toxicity
Hypercholesterolemia
Oxidative stress
Mitochondria
Macrophage
Atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324003300

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http://www.sciencedirect.com/science/article/pii/S0147651324003300

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