Developmental decrease of entorhinal-hippocampal communication in immune-challenged DISC1 knockdown mice
The authors show that mice that mimic the dual genetic-environmental etiology of psychiatric risk have poor lateral entorhinal cortex-dependent recognition memory already at pre-juvenile age and abnormal communication within LECHP-PFC networks throughout development.
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-27114-w |