Developmental decrease of entorhinal-hippocampal communication in immune-challenged DISC1 knockdown mice

The authors show that mice that mimic the dual genetic-environmental etiology of psychiatric risk have poor lateral entorhinal cortex-dependent recognition memory already at pre-juvenile age and abnormal communication within LECHP-PFC networks throughout development.

Bibliographic Details
Main Authors: Xiaxia Xu, Lingzhen Song, Rebecca Kringel, Ileana L. Hanganu-Opatz
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27114-w