Developmental decrease of entorhinal-hippocampal communication in immune-challenged DISC1 knockdown mice
The authors show that mice that mimic the dual genetic-environmental etiology of psychiatric risk have poor lateral entorhinal cortex-dependent recognition memory already at pre-juvenile age and abnormal communication within LECHP-PFC networks throughout development.
Main Authors: | Xiaxia Xu, Lingzhen Song, Rebecca Kringel, Ileana L. Hanganu-Opatz |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-27114-w |
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