T cells with increased responsiveness cause obesity in mice without diet intervention

T cells with increased responsiveness cause obesity in mice without diet intervention

Summary: Obesity is a complex multicausal disease that can cause morbidity and mortality, and there is need for improved knowledge on the underlying mechanisms. Using a mouse model of increased T cell responsiveness, we show that development of obesity can be driven by immune cells. This was confirm...

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Bibliographic Details
Main Authors: Ida Gregersen, Xiang Y. Kong, Sander Kooijman, Håvard Foyn, Helene Grannes, Maria B. Olsen, Anna M. Lone, Kuan Yang, Ana Quiles-Jiménez, Marianne Tran, Jonas Øgaard, Filip M. Segers, Azita Rashidi, Ellen Lund Sagen, Knut H. Lauritzen, Amanda C.M. Pronk, Jan Freark de Boer, Kirsten B. Holven, Espen Melum, Pål Aukrust, Kjetil Taskén, Sverre Holm, Patrick C.N. Rensen, Tuva B. Dahl, Bente Halvorsen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Immunology
Nutrition
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224006928

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http://www.sciencedirect.com/science/article/pii/S2589004224006928

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