Boosting scRNA-seq data clustering by cluster-aware feature weighting
Abstract Background The rapid development of single-cell RNA sequencing (scRNA-seq) enables the exploration of cell heterogeneity, which is usually done by scRNA-seq data clustering. The essence of scRNA-seq data clustering is to group cells by measuring the similarities among genes/transcripts of c...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04033-7 |