Reassembling a cannon in the DNA defense arsenal: Genetics of StySA, a BREX phage exclusion system in Salmonella lab strains.

Understanding mechanisms that shape horizontal exchange in prokaryotes is a key problem in biology. A major limit on DNA entry is imposed by restriction-modification (RM) processes that depend on the pattern of DNA modification at host-specified sites. In classical RM, endonucleolytic DNA cleavage f...

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Bibliographic Details
Main Authors: Julie Zaworski, Oyut Dagva, Julius Brandt, Chloé Baum, Laurence Ettwiller, Alexey Fomenkov, Elisabeth A Raleigh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009943