CCR1 mediates Müller cell activation and photoreceptor cell death in macular and retinal degeneration
Mononuclear cells are involved in the pathogenesis of retinal diseases, including age-related macular degeneration (AMD). Here, we examined the mechanisms that underlie macrophage-driven retinal cell death. Monocytes were extracted from patients with AMD and differentiated into macrophages (hMdɸs),...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-10-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/81208 |