CCR1 mediates Müller cell activation and photoreceptor cell death in macular and retinal degeneration

Mononuclear cells are involved in the pathogenesis of retinal diseases, including age-related macular degeneration (AMD). Here, we examined the mechanisms that underlie macrophage-driven retinal cell death. Monocytes were extracted from patients with AMD and differentiated into macrophages (hMdɸs),...

Full description

Bibliographic Details
Main Authors: Sarah Elbaz-Hayoun, Batya Rinsky, Shira Hagbi-Levi, Michelle Grunin, Itay Chowers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/81208