CCR1 mediates Müller cell activation and photoreceptor cell death in macular and retinal degeneration

CCR1 mediates Müller cell activation and photoreceptor cell death in macular and retinal degeneration

Mononuclear cells are involved in the pathogenesis of retinal diseases, including age-related macular degeneration (AMD). Here, we examined the mechanisms that underlie macrophage-driven retinal cell death. Monocytes were extracted from patients with AMD and differentiated into macrophages (hMdɸs),...

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Bibliographic Details
Main Authors: Sarah Elbaz-Hayoun, Batya Rinsky, Shira Hagbi-Levi, Michelle Grunin, Itay Chowers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
CCR1
macrophage
Müller cell
atrophic AMD
retina
gliosis
Online Access:https://elifesciences.org/articles/81208

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