Dynamics of Pathological and Virological Findings During Experimental Calpox Virus Infection of Common Marmosets (Callithrix jacchus)

Dynamics of Pathological and Virological Findings During Experimental Calpox Virus Infection of Common Marmosets (Callithrix jacchus)

Experimental intranasal infection of marmosets (Callithrix jacchus) with calpox virus results in fatal disease. Route and dose used for viral inoculation of the test animals mimics the natural transmission of smallpox, thus representing a suitable model to study pathogenesis and to evaluate new vacc...

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Bibliographic Details
Main Authors: Anne Schmitt, Li Lin Gan, Ahmed Abd El Wahed, Tingchuan Shi, Heinz Ellerbrok, Franz-Josef Kaup, Christiane Stahl-Hennig, Kerstin Mätz-Rensing
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Viruses
Subjects:
calpox virus
common marmoset
immunohistochemistry
nonhuman primate
orthopoxvirus
pathogenesis
transmission electron microscopy
virus infection
Online Access:https://www.mdpi.com/1999-4915/9/12/363

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https://www.mdpi.com/1999-4915/9/12/363

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