INTS7–ABCD3 Interaction Stimulates the Proliferation and Osteoblastic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Suppressing Oxidative Stress

INTS7–ABCD3 Interaction Stimulates the Proliferation and Osteoblastic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Suppressing Oxidative Stress

Increased adipocyte and decreased osteoblast differentiation, combined with the ectopic proliferation of bone marrow mesenchymal stem cells (BM-MSCs), represent the primary causes of osteoporosis. The dysregulation of numerous intracellular bioactive factors is responsible for the aberrant different...

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Bibliographic Details
Main Authors: Yubo Liu, Xiao Yu, Anquan Huang, Xiangxin Zhang, Yijun Wang, Wei Geng, Renjie Xu, Suoyuan Li, Hui He, Bo Zheng, Guangxiang Chen, Yaozeng Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Physiology
Subjects:
bone marrow mesenchymal stem cells (BM-MSCs)
INTS7
ABCD3
proliferation
osteoblastic differentiation
adipogenic differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.758607/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.758607/full

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