BBOX1 promotes triple-negative breast cancer progression by controlling IP3R3 stability

BBOX1 promotes triple-negative breast cancer progression by controlling IP3R3 stability

Limited therapeutic options impede the clinical outcome of triple-negative breast cancer (TNBC). Our recent study uncovered a novel signaling pathway implicating gamma-butyrobetaine hydroxylase 1 (BBOX1) in the control of cell growth in TNBC, via inositol 1, 4, 5-trisphosphate receptor type 3 (IP3R3...

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Bibliographic Details
Main Authors: Chengheng Liao, Qing Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Molecular & Cellular Oncology
Subjects:
tnbc
2-og dependent enzyme
therapeutic target
Online Access:http://dx.doi.org/10.1080/23723556.2020.1813526

Internet

http://dx.doi.org/10.1080/23723556.2020.1813526

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