Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus

Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus

Summary: A simple and robust cell culture system is essential for generating authentic SARS-CoV-2 stocks for evaluation of viral pathogenicity, screening of antiviral compounds, and preparation of inactivated vaccines. Evidence suggests that Vero E6, a cell line commonly used in the field to grow SA...

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Bibliographic Details
Main Authors: Da-Yuan Chen, Jacquelyn Turcinovic, Shuchen Feng, Devin J. Kenney, Chue Vin Chin, Manish C. Choudhary, Hasahn L. Conway, Marc Semaan, Brianna J. Close, Alexander H. Tavares, Scott Seitz, Nazimuddin Khan, Sebastian Kapell, Nicholas A. Crossland, Jonathan Z. Li, Florian Douam, Susan C. Baker, John H. Connor, Mohsan Saeed
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Methodology in biological sciences
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223007113

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http://www.sciencedirect.com/science/article/pii/S2589004223007113

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