Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle

Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle

Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility. STIM1 occupies space in the junctional SR membra...

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Bibliographic Details
Main Authors: Hengtao Zhang, Victoria Graham Bryson, Chaojian Wang, TianYu Li, Jaclyn P. Kerr, Rebecca Wilson, Deborah M. Muoio, Robert J. Bloch, Christopher Ward, Paul B. Rosenberg
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-09-01
Series:JCI Insight
Subjects:
Muscle biology
Online Access:https://doi.org/10.1172/jci.insight.143472

Internet

https://doi.org/10.1172/jci.insight.143472

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