Live-Cell FRET Reveals that Malaria Nutrient Channel Proteins CLAG3 and RhopH2 Remain Associated throughout Their Tortuous Trafficking

ABSTRACT Malaria parasites increase their host erythrocyte’s permeability to various nutrients, fueling intracellular pathogen development and replication. The plasmodial surface anion channel (PSAC) mediates this uptake and is linked to the parasite-encoded RhopH complex, consisting of CLAG3, RhopH...

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Bibliographic Details
Main Authors: Moaz Ahmad, Javier Manzella-Lapeira, Gagandeep Saggu, Daisuke Ito, Joseph A. Brzostowski, Sanjay A. Desai
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01354-20