Patulin Stimulates Progenitor Leydig Cell Proliferation but Delays Its Differentiation in Male Rats during Prepuberty

Patulin is a mycotoxin with potential reproductive toxicity. We explored the impact of patulin on Leydig cell (LC) development in male rats. Male Sprague Dawley rats (21 days postpartum) were gavaged patulin at doses of 0.5, 1, and 2 mg/kg/day for 7 days. Patulin markedly lowered serum testosterone...

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Bibliographic Details
Main Authors: Huitao Li, Ming Su, Hang Lin, Jingjing Li, Shaowei Wang, Lei Ye, Xingwang Li, Renshan Ge
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/15/9/581