Combined resting state-fMRI and calcium recordings show stable brain states for task-induced fMRI in mice under combined ISO/MED anesthesia

For fMRI in animal models, the combination of low-dose anesthetic, isoflurane (ISO), and the sedative medetomidine (MED) has recently become an advocated regimen to achieve stable neuronal states and brain networks in rats that are required for reliable task-induced BOLD fMRI. However, in mice the t...

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Bibliographic Details
Main Authors: Bruno Pradier, Lydia Wachsmuth, Nina Nagelmann, Daniel Segelcke, Silke Kreitz, Andreas Hess, Esther M. Pogatzki-Zahn, Cornelius Faber
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:NeuroImage
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921008995