Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation

Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation

Aims: This study aimed to investigate whether human umbilical cord mesenchymal stem cells (UC-MSCs) can prevent articular cartilage degradation and explore the underlying mechanisms in a rat osteoarthritis (OA) model induced by monosodium iodoacetate (MIA). Methods: Human UC-MSCs were characterize...

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Bibliographic Details
Main Authors: Quan Zhang, E. Xiang, Wei Rao, Ya Qi Zhang, Cui Hong Xiao, Chang Yong Li, Bing Han, Dongcheng Wu
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-03-01
Series:Bone & Joint Research
Subjects:
human umbilical cord mesenchymal stem cells
osteoarthritis
cartilage degradation
inflammatory response
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.103.BJR-2020-0206.R2

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.103.BJR-2020-0206.R2

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