Nutritional Interventions with <em>Bacillus coagulans</em> Improved Glucose Metabolism and Hyperinsulinemia in Mice with Acute Intermittent Porphyria

Nutritional Interventions with <em>Bacillus coagulans</em> Improved Glucose Metabolism and Hyperinsulinemia in Mice with Acute Intermittent Porphyria

Acute intermittent porphyria (AIP) is a metabolic disorder caused by mutations in the porphobilinogen deaminase (PBGD) gene, encoding the third enzyme of the heme synthesis pathway. Although AIP is characterized by low clinical penetrance (~1% of PBGD mutation carriers), patients with clinically sta...

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Bibliographic Details
Main Authors: Miriam Longo, Daniel Jericó, Karol M. Córdoba, José Ignacio Riezu-Boj, Raquel Urtasun, Isabel Solares, Ana Sampedro, María Collantes, Ivan Peñuelas, María Jesús Moreno-Aliaga, Matías A. Ávila, Elena Di Pierro, Miguel Barajas, Fermín I. Milagro, Paola Dongiovanni, Antonio Fontanellas
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
glucose homeostasis
gut microbiome
hepatic porphyria
insulin resistance
metabolic disease
nutritional intervention
Online Access:https://www.mdpi.com/1422-0067/24/15/11938

Internet

https://www.mdpi.com/1422-0067/24/15/11938

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