Association between Polymorphisms in CFH, ARMS2, CFI, and C3 Genes and Response to Anti-VEGF Treatment in Neovascular Age-Related Macular Degeneration

Association between Polymorphisms in CFH, ARMS2, CFI, and C3 Genes and Response to Anti-VEGF Treatment in Neovascular Age-Related Macular Degeneration

Neovascular age-related macular degeneration (nAMD) is the leading cause of vision loss in the elderly. The gold standard of nAMD treatment is intravitreal injections of vascular endothelial growth factor (VEGF) inhibitors. Genetic factors may influence the response to anti-VEGF therapy and result i...

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Bibliographic Details
Main Authors: Oyuna S. Kozhevnikova, Anzhella Zh. Fursova, Anna S. Derbeneva, Ida F. Nikulich, Mikhail S. Tarasov, Vasiliy A. Devyatkin, Yulia V. Rumyantseva, Darya V. Telegina, Nataliya G. Kolosova
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
age-related macular degeneration
neovascularization
anti-VEGF therapy
regulatory SNP
pharmacogenomics
Online Access:https://www.mdpi.com/2227-9059/10/7/1658

Internet

https://www.mdpi.com/2227-9059/10/7/1658

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