Pathogenicity and rapid growth kinetics of feline immunodeficiency virus are linked to 3' elements.

Chimeric viruses constructed between a highly pathogenic Feline Immunodeficiency Virus isolate (FIV-C36) and a less pathogenic but neurotropic strain (FIV-PPR) have been used to map viral genetic determinants of in vivo pathogenicity. Chimeric virus FIV-PCenv, which contains FIV-C36 genome from the...

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Bibliographic Details
Main Authors: Jesse Thompson, Martha MacMillan, Karen Boegler, Charles Wood, John H Elder, Sue VandeWoude
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3162592?pdf=render