Polymorphonuclear Cells Show Features of Dysfunctional Activation During Fatal Sepsis

Polymorphonuclear Cells Show Features of Dysfunctional Activation During Fatal Sepsis

Sepsis and septic shock remain leading causes of morbidity and mortality for patients in the intensive care unit. During the early phase, immune cells produce various cytokines leading to prompt activation of the immune system. Polymorphonuclear leukocytes (PMNs) respond to different signals produci...

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Bibliographic Details
Main Authors: Marcela Hortová-Kohoutková, Marco De Zuani, Petra Lázničková, Kamila Bendíčková, Ondřej Mrkva, Ivana Andrejčinová, Alexandra Mýtniková, Ondřej Polanský, Kamila Kočí, Veronika Tomášková, Vladimír Šrámek, Martin Helán, Jan Frič
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
sepsis
polymorphonuclears
septic shock
transcriptomics
proteomics
dysfunctionality
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.741484/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.741484/full

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