Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells

Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells

Introduction Plasmacytoid dendritic cells (pDCs) are the main producers of type I interferon (IFN) in SLE. pDCs express high secretory carrier membrane protein 5 (SCAMP5). Recent work in transfected HEK cells connects SCAMP5 to the type I IFN secretory pathway. To further study the role of SCAMP5 in...

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Bibliographic Details
Main Authors: Timothy R D J Radstake, Marianne Boes, Emmerik F A Leijten, Juliëtte N Pouw, Michel A M Olde Nordkamp, Tom G O'Toole
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/9/1/e000680.full

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https://lupus.bmj.com/content/9/1/e000680.full

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