KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1

KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1

Summary: Human spermatogonial stem cells (SSCs) are essential for spermatogenesis and male fertility. However, molecular mechanisms regulating fate determinations of human SSCs remain elusive. In this study, we revealed that KLF2 decreased the proliferation, DNA synthesis, and colonization of human...

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Bibliographic Details
Main Authors: Wei Chen, Yinghong Cui, Chunyun Li, Caimei He, Li Du, Wei Liu, Zuping He
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Natural sciences
Biological sciences
Biochemistry
Physiology
Endocrinology
Male reproductive endocrinology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224002451

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http://www.sciencedirect.com/science/article/pii/S2589004224002451

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