1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors

1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors

A series of new analogs of nitrogen mustards (<b>4a</b>–<b>4</b><b>h</b>) containing the 1,3,5-triazine ring substituted with dipeptide residue were synthesized and evaluated for the inhibition of both acetylcholinesterase (AChE) and <i>β</i>-secretase...

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Bibliographic Details
Main Authors: Dawid Maliszewski, Agnieszka Wróbel, Beata Kolesińska, Justyna Frączyk, Danuta Drozdowska
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
acetylcholinesterase
<i>β</i>-secretase
nitrogen mustards
1,3,5-triazine
Online Access:https://www.mdpi.com/1420-3049/26/13/3942

Internet

https://www.mdpi.com/1420-3049/26/13/3942

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