Synthetic Routes and Clinical Application of Representative Small-Molecule EGFR Inhibitors for Cancer Therapy

Synthetic Routes and Clinical Application of Representative Small-Molecule EGFR Inhibitors for Cancer Therapy

The epidermal growth factor receptor (EGFR) plays a pivotal role in cancer therapeutics, with small-molecule EGFR inhibitors emerging as significant agents in combating this disease. This review explores the synthesis and clinical utilization of EGFR inhibitors, starting with the indispensable role...

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Bibliographic Details
Main Authors: Ya-Tao Wang, Peng-Cheng Yang, Jing-Yi Zhang, Jin-Feng Sun
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
EGFR
tyrosine kinase inhibitors (TKIs)
small molecule
synthetic routes
application
Online Access:https://www.mdpi.com/1420-3049/29/7/1448

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https://www.mdpi.com/1420-3049/29/7/1448

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