Translational concepts of mGluR5 in synaptic diseases of the brain

Translational concepts of mGluR5 in synaptic diseases of the brain

The G-protein coupled receptor family of glutamate receptors, termed metabotropic glutamate receptors (mGluRs), are implicated in numerous cellular mechanisms ranging from neural development to the processing of cognitive, sensory, and motor information. Over the last decade, multiple mGluR-related...

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Bibliographic Details
Main Authors: Thomas M Piers, Dong Hyun eKim, Byeong C Kim, Philip eRegan, Daniel John Whitcomb, Kwangwook eCho
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Pharmacology
Subjects:
Clinical Trials as Topic
Alzheimer's disease
mGluR5
scaffolding proteins
synaptic disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00199/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00199/full

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