Alpha-tocopherol-loaded polycaprolactone nanoparticles improve the inflammation and systemic oxidative stress of arthritic rats

Alpha-tocopherol-loaded polycaprolactone nanoparticles improve the inflammation and systemic oxidative stress of arthritic rats

Background and aim: The present study investigated the effects of orally administered α-tocopherol-loaded polycaprolactone nanoparticles on the articular inflammation and systemic oxidative status of middle-aged Holtzman rats with Freund's adjuvant-induced polyarthritis, a model for rheumatoid...

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Bibliographic Details
Main Authors: Lucas S. Moreira, Any Carolina Chagas, Ana Paula Ames-Sibin, Vanesa O. Pateis, Odinei H. Gonçalves, Francielli Maria S. Silva-Comar, Luzmarina Hernandes, Anacharis B. Sá-Nakanishi, Lívia Bracht, Ciomar A. Bersani-Amado, Adelar Bracht, Jurandir F. Comar
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Adjuvant-induced arthritis
Rheumatoid arthritis
α-tocopherol
Polycaprolactone
Oxidative status
Antioxidant status
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411021001437

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http://www.sciencedirect.com/science/article/pii/S2225411021001437

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