Patient-specific image-based bone marrow dosimetry in Lu-177-[DOTA0,Tyr3]-Octreotate and Lu-177-DKFZ-PSMA-617 therapy: investigation of a new hybrid image approach

Patient-specific image-based bone marrow dosimetry in Lu-177-[DOTA0,Tyr3]-Octreotate and Lu-177-DKFZ-PSMA-617 therapy: investigation of a new hybrid image approach

Abstract Background The bone marrow (BM) is a main organ at risk in Lu-177-PSMA-617 therapy of prostate cancer and Lu-177-Octreotate therapy of neuroendocrine tumours. BM dosimetry is challenging and time-consuming, as different sequential quantitative measurements must be combined. The BM absorbed...

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Bibliographic Details
Main Authors: Astrid Gosewisch, Andreas Delker, Sebastian Tattenberg, Harun Ilhan, Andrei Todica, Julia Brosch, Lena Vomacka, Anika Brunegraf, Franz Josef Gildehaus, Sibylle Ziegler, Peter Bartenstein, Guido Böning
Format: Article
Language:English
Published: SpringerOpen 2018-08-01
Series:EJNMMI Research
Subjects:
Radionuclide therapy
Bone marrow
Dosimetry
Hybrid imaging
Lutetium-177
Prostate cancer
Online Access:http://link.springer.com/article/10.1186/s13550-018-0427-z

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http://link.springer.com/article/10.1186/s13550-018-0427-z

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