Protocol for the selection of Mycobacterium tuberculosis spontaneous resistant mutants to d-cycloserine

Mycobacterium tuberculosis (MTB) is known for its adaptive capability in developing resistance to antibiotics, through the selection of spontaneous mutations that arise during treatment. Generating spontaneous antibiotic-resistant mutants in vitro is challenging but necessary for studying this pheno...

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Bibliographic Details
Main Authors: Alejandra Osorio-González, Nataly Álvarez, Teresa Realpe, Jaime Robledo
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016124001444