Neurotrophins and Neuropathic Pain: Role in Pathobiology

Neurotrophins and Neuropathic Pain: Role in Pathobiology

Neurotrophins (NTs) belong to a family of trophic factors that regulate the survival, growth and programmed cell death of neurons. In mammals, there are four structurally and functionally related NT proteins, viz. nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 an...

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Bibliographic Details
Main Authors: Nemat Khan, Maree T. Smith
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
allodynia
BDNF
central sensitisation
NGF
NT-3
NT-4
neurotrophins
neuropathic pain
p75NTR
neurotrophic tyrosine kinase (Trk) receptor
Online Access:http://www.mdpi.com/1420-3049/20/6/10657

Internet

http://www.mdpi.com/1420-3049/20/6/10657

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