sPLA2 Wobbles on the Lipid Bilayer between Three Positions, Each Involved in the Hydrolysis Process

Secreted phospholipases A2 (sPLA2s) are peripheral membrane enzymes that hydrolyze phospholipids in the <i>sn-2</i> position. The action of sPLA2 is associated with the work of two active sites. One, the interface binding site (IBS), is needed to bind the enzyme to the membrane surface....

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Bibliographic Details
Main Authors: Natalia Kuzmina, Pavel Volynsky, Ivan Boldyrev, Anna Alekseeva
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/14/10/669