Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model

Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model

Urinary exosomes, small extracellular vesicles present in urine, are secreted from all types of renal epithelial cells. Aquaporin-2 (AQP2), a vasopressin-regulated water channel protein, is known to be selectively excreted into the urine through exosomes (UE-AQP2), and its renal expression is decrea...

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Bibliographic Details
Main Authors: Ahmed Abdeen, Hiroko Sonoda, Ayaha Kaito, Sayaka Oshikawa-Hori, Naruki Fujimoto, Masahiro Ikeda
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
urinary exosomes
aquaporin-2
puromycin aminonucleoside
nephrotic syndrome
nephrotoxicity
Online Access:https://www.mdpi.com/1422-0067/21/12/4288

Internet

https://www.mdpi.com/1422-0067/21/12/4288

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