Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells

Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells

ABSTRACTThe global pandemic of coronavirus disease 2019 (COVID-19) is a disaster for human society. A convenient and reliable neutralization assay is very important for the development of vaccines and novel drugs. In this study, a G protein-deficient vesicular stomatitis virus (VSVdG) bearing a trun...

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Bibliographic Details
Main Authors: Hua-Long Xiong, Yang-Tao Wu, Jia-Li Cao, Ren Yang, Ying-Xia Liu, Jian Ma, Xiao-Yang Qiao, Xiang-Yang Yao, Bao-Hui Zhang, Ya-Li Zhang, Wang-Heng Hou, Yang Shi, Jing-Jing Xu, Liang Zhang, Shao-Juan Wang, Bao-Rong Fu, Ting Yang, Sheng-Xiang Ge, Jun Zhang, Quan Yuan, Bao-Ying Huang, Zhi-Yong Li, Tian-Ying Zhang, Ning-Shao Xia
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
pseudovirus
neutralization assay
vesicular stomatitis virus
VSV-SARS-CoV-2
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1815589

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https://www.tandfonline.com/doi/10.1080/22221751.2020.1815589

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