Acetylcholinesterase-Inhibiting Activity of Salicylanilide <em>N</em>-Alkylcarbamates and Their Molecular Docking

Acetylcholinesterase-Inhibiting Activity of Salicylanilide <em>N</em>-Alkylcarbamates and Their Molecular Docking

A series of twenty-five novel salicylanilide <em>N</em>-alkylcarbamates were investigated as potential acetylcholinesterase inhibitors. The compounds were tested for their ability to inhibit acetylcholinesterase (AChE) from electric eel (<em>Electrophorus el...

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Bibliographic Details
Main Authors: Josef Jampilek, Juana Monreal-Ferriz, Jarmila Vinsova, Karel Pauk, Jan Vanco, Sarka Stepankova, Ales Imramovsky
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Molecules
Subjects:
4-chloro-2-(chlorophenylcarbamoyl)phenyl alkylcarbamates
<em>in vitro</em> acetyl-cholinesterase inhibition
lipophilicity
molecular docking
Online Access:http://www.mdpi.com/1420-3049/17/9/10142

Internet

http://www.mdpi.com/1420-3049/17/9/10142

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