Significant impact of the MTHFR polymorphisms and haplotypes on male infertility risk.

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) converts 5,10-methylene tetrahydrofolate to 5-methyl tetrahydrofolate and affects the activity of cellular cycles participating in nucleotide synthesis, DNA repair, genome stability, maintenance of methyl pool, and gene regulation. Genetically...

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Bibliographic Details
Main Authors: Nishi Gupta, Saumya Sarkar, Archana David, Pravin Kumar Gangwar, Richa Gupta, Gita Khanna, Satya Narayan Sankhwar, Anil Khanna, Singh Rajender
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715460?pdf=render