Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity

Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity

Immune recognition by T lymphocytes and natural killer (NK) cells is in large part dependent on the identification of cell surface MHC molecules bearing peptides generated from either endogenous (MHC I) or exogenous (MHC II) dependent pathways. This review focuses on MHC I molecules that coordinatel...

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Bibliographic Details
Main Authors: David H. Margulies, Daniel K. Taylor, Jiansheng Jiang, Lisa F. Boyd, Javeed Ahmad, Michael G. Mage, Kannan Natarajan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
Antigen presentation
peptide loading complex (PLC)
tapasin
TAP binding protein
related (TAPBPR)
major histocompatibility complex (MHC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.859782/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.859782/full

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