Design and analysis of umbrella trials: Where do we stand?

BackgroundThe efficiencies that master protocol designs can bring to modern drug development have seen their increased utilization in oncology. Growing interest has also resulted in their consideration in non-oncology settings. Umbrella trials are one class of master protocol design that evaluates m...

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Bibliographic Details
Main Authors: Luke O. Ouma, James M. S. Wason, Haiyan Zheng, Nina Wilson, Michael Grayling
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1037439/full