Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection

Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection

ABSTRACT Ocular herpes simplex virus 1 (HSV-1) infection leads to an immunopathogenic disease called herpes stromal keratitis (HSK), in which CD4+ T cell-driven inflammation contributes to irreversible damage to the cornea. Herpesvirus entry mediator (HVEM) is an immune modulator that activates stim...

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Bibliographic Details
Main Authors: Seo J. Park, Rachel E. Riccio, Sarah J. Kopp, Igal Ifergan, Stephen D. Miller, Richard Longnecker
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
BTLA
CD160
HSV
HVEM
immunopathogenesis
herpesvirus stromal keratitis
Online Access:https://journals.asm.org/doi/10.1128/mBio.00790-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00790-20

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