Minimal Kidney Disease Phenotype in Heterozygous Null Mice

Background: Shroom family member 3 (SHROOM3) encodes an actin-associated protein that regulates epithelial morphology during development. Several genome-wide association studies (GWAS) have identified genetic variances primarily in the 5’ region of SHROOM3, associated with chronic kidney disease (CK...

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Bibliographic Details
Main Authors: Allison Lawlor, Kristina Cunanan, Joanna Cunanan, Amy Paul, Hadiseh Khalili, Doyun Ko, Ahsan Khan, Robert Gros, Thomas Drysdale, Darren Bridgewater
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Canadian Journal of Kidney Health and Disease
Online Access:https://doi.org/10.1177/20543581231165716