Synthesis of two PNA thymine monomers based on L-alanine and glycine

Synthesis of two PNA thymine monomers based on L-alanine and glycine

Effective preparative synthesis of two thymine containing monomers of polyamide DNA-mimics based on L-alanine and glycine is presented. The results of investigation are more effective steps for allyl ester protective group incorporation and coupling of thymin-1-yl acetic acid with pseudopeptide inte...

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Bibliographic Details
Main Authors: M. A. Lyanov, Yu. G. Kirillova, D. I. Prokhorov, A. I. Lyutik, O. V. Esipova, V. I. Shvets
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2010-02-01
Series:Тонкие химические технологии
Subjects:
peptide nucleic acids (pna)
chiral monomers of pna
pseudopeptides
mitsunobu reaction
Online Access:https://www.finechem-mirea.ru/jour/article/view/1025

Internet

https://www.finechem-mirea.ru/jour/article/view/1025

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